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Brain tumours kill more children and adults under the age of 40 than any other cancer

Collaboration leads to exciting new clinical trial

by Crispin Zeeman
One of the challenges to finding a cure for brain tumours is to identify specific changes between the cancer cells and normal cells within the brain which can act as targets for the action of new therapies. Schwannoma and meningioma are two types of low-grade brain tumour being investigated by the research team at our Plymouth University Centre of Excellence. 

The team there is led by Professor Oliver Hanemann. Working closely in collaboration with Dr Nelofer Syed – who heads up the research team at our Imperial College Centre of Excellence – Prof Hanemann published a paper recently in the journal EBioMedicine, comparing the profile of these tumours and normal cells. 

Using state-of-the-art techniques, they identified specific changes in the tumour cells and, significantly, have determined how to overcome the changes, stopping the tumour in its tracks! This exciting research development has brought a focus on certain drugs already used for kidney and liver cancer but never before for brain tumours.

Moving quickly is a ‘trademark’ of our Plymouth team and this discovery is now forming the basis for a new clinical trial. We’ll bring you more news of this trial when we have it.
This article originally appeared in Believe - Issue 009 - Summer 2017.